The relationship between childhood trauma and clinical characteristics in ultra-high risk for psychosis youth

C de Vos; A Thompson; P Amminger; S Bendall; L de Haan; J Hartmann; S Lavoie; C Markulev; P McGorry; D Nieman; L Phillips; U Reininghaus; HP Yuen; A Yung; B Nelson

Journal article

The relationship between childhood trauma and clinical characteristics in ultra-high risk for psychosis youth

C de Vos, A Thompson, P Amminger, S Bendall, L de Haan, J Hartmann, S Lavoie, C Markulev, P McGorry, D Nieman, L Phillips, U Reininghaus, HP Yuen, A Yung, B Nelson

Psychosis | ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD | Published : 2019

DOI: 10.1080/17522439.2019.1582686

Abstract

Mounting evidence suggests that a history of childhood trauma (CT) is associated with an increased risk of developing a psychotic disorder. Whereas the majority of studies in this area have focused on onset (“transition”) of psychosis as their primary outcome, few studies have examined the impact of CT on distress associated with attenuated psychotic symptoms (APS) and on diagnostic outcomes other than transition to psychosis. The current study presents data from 81 ultra-high risks (UHR) for psychosis patients who were followed-up for 12 months and who were assessed for a history of CT, severity and distress associated with APS, general psychopathology, functioning and transition to psychos..

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University of Melbourne Researchers

Andrew Thompson Author

Paul Amminger Author

Sarah Bendall Author

Suzie Lavoie Author

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Grants

Awarded by Stanley Medical Research Institute

Funding Acknowledgements

The NEURAPRO trial was supported by grants from the Stanley Medical Research Institute (07TGF-1102) and from the National Health and Medical Research Council of Australia (NHMRC; 566529). Dr McGorry was supported by a NHRMC Senior Principal Research Fellowship (1060996), and Drs Amminger, Nelson and Yung were supported by NHMRC Senior Research Fellowships (566593, 1137687 and 1080963 respectively). Dr Hartmann was supported by a University of Melbourne McKenzie Postdoctoral Fellowship. The study was also supported by a Melbourne Health Grant in Aid.